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(923-FG7) 伯楨生物(bioGenous) Recombinant Human FGF7

欄目:生長(cháng)因子及小分子(用于類(lèi)器官培養)
分享到:
(923-FG7) 伯楨生物(bioGenous) Recombinant Human FGF7
貨號:923-FG7-1mg;
923-FG7-100μg;
品牌: 伯楨生物(bioGenous)

產(chǎn)品介紹


產(chǎn)品編號

產(chǎn)品名稱(chēng)

    包裝規格    

     價(jià)格    

      923-FG7-1mg       

     Recombinant Human FGF7     

1mg

10494

  923-FG7-100μg 

Recombinant Human FGF7

100μg

1799


DESCRIPTION

Background:

FGF-7 (fibroblast growth factor-7) is one of 22 known members of the mouse FGF family of secreted proteins that plays a key role in development, morphogenesis, angiogenesis, wound healing, and tumorigenesis[1].FGF-7 promotes cell migration and invasion, and mediates melanocyte transfer to keratinocytes upon UVB radiation[2]. It has been used ectopically to avoid chemotherapy-induced oral mucositis in patients with hematological malignancies. Deletion of FGF-7 affects kidney development, producing abnormally small ureteric buds and fewer nephrons[3] . It also impedes hair follicle differentiation [4]. The 194 amino acid (aa) FGF-7 precursor contains a 31 aa signal sequence and, like all other FGFs, an ~120 aa beta -trefoil scaffold that includes receptor- and heparin-binding sites.


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